The most common side effects from antiretroviral medications (ARVs) in children are digestive problems such as diarrhea and nausea, which can often be managed with dietary changes. However other possible side effect are: 

• Fatigue
• Anemia
• Lipodystrophy (fat loss in arms, legs and face; fat gain in the stomach or behind the neck; and increases in fats (cholesterol) and sugar (glucose) in the blood. These changes may increase the risk of heart attack or stroke. )
• Skin Problems (Some medications cause rashes, others cause dry skin or hair loss. Moisturizers help some skin problems.)
• Neuropathy (a painful condition caused by nerve damage, which normally starts in the feet or hands.)
• Mitochondrial Toxicity (damage to structures inside the cells. It might cause neuropathy or kidney damage, and can cause a buildup of lactic acid in the body)
• Bone Problems (Bones can lose their mineral content and become brittle. A loss of blood supply can cause hip problems. Get enough calcium from food and supplements. Weight-bearing exercise like walking or weight lifting can be helpful.)

Most people who take ARVs have some side effects. However, don't assume your child will get every side effect you hear about! Do not assume that taking ART (antiretroviral therapy) means you have to put up with the side effects either. If side effects continue for more than a few months, or they affect your child's quality of life, talk to your health care provider about changing the particular drugs. There are over 30 HIV+ medications available and some may work better than others for different individuals.